Detalhe da pesquisa
1.
Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.
Cell
; 184(2): 384-403.e21, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450205
2.
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.
Cell
; 183(5): 1436-1456.e31, 2020 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33212010
3.
Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns.
Cell
; 173(2): 499-514.e23, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29576454
4.
Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer.
Mol Cell
; 81(15): 3048-3064.e9, 2021 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216543
5.
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase.
Cell
; 144(5): 703-18, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21376233
6.
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.
Cell
; 137(5): 835-48, 2009 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19490893
7.
Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.
Nature
; 556(7700): 249-254, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29615789
8.
The spliceosome is a therapeutic vulnerability in MYC-driven cancer.
Nature
; 525(7569): 384-8, 2015 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26331541
9.
A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach.
J Neurosci
; 38(43): 9286-9301, 2018 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249792
10.
RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1.
Nature
; 498(7454): 325-331, 2013 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719381
11.
Plk2 regulates mitotic spindle orientation and mammary gland development.
Development
; 141(7): 1562-71, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24598160
12.
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.
Mol Cell
; 32(5): 718-26, 2008 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19061646
13.
Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase.
Breast Cancer Res
; 16(5): 430, 2014 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25212826
14.
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.
Nature
; 452(7185): 370-4, 2008 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18354483
15.
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Proc Natl Acad Sci U S A
; 108(9): 3665-70, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21307310
16.
Erratum: iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells.
iScience
; 27(5): 109727, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38646177
17.
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Nat Cell Biol
; 25(4): 528-539, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024683
18.
iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells.
iScience
; 26(7): 107059, 2023 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37360684
19.
Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation.
Elife
; 112022 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36043466
20.
Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics.
Cancer Res Commun
; 1(3): 178-193, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35156101